This visual compares normal brain network connectivity to disruptions seen in depression, schizophrenia, and ADHD. It highlights how dysfunction in the DMN, SN, and CEN contributes to psychopathology, based on connectome science.

🧠 Mapping Mental Illness: The Human Connectome and Psychopathology

An In-Depth Website Summary of Xia & Heeringa’s “Psychopathology and the Human Connectome” 🔍 Introduction The 21st-century revolution in neuroscience has radically reshaped our understanding of mental illness. No longer seen solely as chemical imbalances or isolated dysfunctions in specific brain regions, psychiatric disorders are now increasingly conceptualized as network-level disorders of the brain—the result of…

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Redefining Schizophrenia: The DSM-5 Shift Towards Dimensional and Valid Diagnosis

The 2013 DSM-5 update marked a major conceptual shift in the diagnosis of schizophrenia, moving away from the traditional subtypes of the DSM-IV (e.g., paranoid, disorganized) and emphasizing a dimensional, criteria-based approach. This foundational article by Tandon et al. outlines the scientific reasoning behind these revisions and their clinical implications. 🔍 What Changed? ❌ Discontinued: Schizophrenia Subtypes…

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